Methodology

Publication
A Machine Learning Classifier for Assigning Individual Patients with Systemic Sclerosis to Intrinsic Molecular Subsets

Franks et al. Arthritis Rheumatol. 2019

Clinical Trial Application

Publication
Machine Learning Predicts Stem Cell Transplant Response in Severe Scleroderma

Franks et al. Ann Rheum Dis. 2020

Publication
Abatacept in Early Diffuse Cutaneous Systemic Sclerosis – Results of a Phase 2 Investigator-Initiated, Multicenter, Double- Blind Randomized Placebo-Controlled Trial

Khanna et al. Arthritis Rheumatol. 2020

Publication
Belimumab for the Treatment of Early Diffuse Systemic Sclerosis

Gordon et al. Arthritis Rheumatol. 2018

Publication
Effect of Anabasum (JBT-101) on Gene Expression in Skin Biopsies from Subjects with Diffuse Cutaneous Systemic Sclerosis (dcSSc) and the Relationship of Baseline Molecular Subsets to Clinical Benefit in the Phase 2 Trial

Martyanov et al. Arthitis Rheumatol. 2017

Publication
Novel lung imaging biomarkers and skin gene expression subsetting in dasatinib treatment of systemic sclerosis-associated interstitial lung disease

Martyanov et al. PLoS One. 2017

Publication
Nilotinib (TasignaTM) in the treatment of early diffuse systemic sclerosis: an open-label, pilot clinical trial

Gordon et al. Arthritis Res Ther. 2015

Publication
Gene expression changes reflect clinical response in a placebo-controlled randomized trial of abatacept in patients with diffuse cutaneous systemic sclerosis

Chakravarty et al. Arthritis Res Ther. 2015

Publication
Molecular Signatures in Skin Associated with Clinical Improvement during Mycophenolate Treatment in Systemic Sclerosis

Hinchcliff et al. J Invest Dermatol. 2013

Meta-Analysis

publication psd ()
A genomic meta-analysis of clinical variables and their association with intrinsic molecular subsets in systemic sclerosis

Franks et al. Rheumatology. 2023

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